Ireland holds one of the largest numbers of asthmatic patients in Europe and worse these cases are on constant rise. The researchers from Trinity College Dublin have uncovered a critical role for a protein called Caspase-11, which was never observed before. Caspase-11 is considered as important in combating bacteria. Now, researchers have observed that its over-activeness can arouse a damaging inflammatory reaction, which eventually leads to the allergic infection in the lungs of asthmatics. Although symptoms of mild asthma can be controlled with current treatment, however, severe asthma is still very difficult to treat. Researchers hope that their research may eventually lead to improved therapeutic options for people living with asthma.