Imagine someone needs a liver transplant, and instead of waiting for a donor, a new one could be grown from their own skin cells. A team of scientists from the University of Pittsburgh has now taken quite a big step towards that future. Researchers developed livers from human cells and then transplanted them into rats. First, human skin cells are assembled from volunteers. Then, these are reprogrammed into induced pluripotent stem cells (IPSCs), essentially turning them to a state where they can be modified into whatever types of cells are required. Future studies will now focus on examining long-term survivability, and other safety interests.