Researchers have recently discovered that the mosquitoes that carry malaria are becoming resistant to insecticides. A protein called SAP2 situated in the insect’s legs helps them to sense toxins through their legs. The resistance mechanism is constantly reducing the efficiency of new insecticide-treated bed nets containing the synergist piperonyl butoxide (PBO) as well as pyrethroid insecticides. Researchers believe that the newly discovered resistance mechanism will be helpful to monitor insecticide resistance and the development of improved insecticides to prevent the spread of malaria.